Detalhe da pesquisa
1.
Ethylmalonic acid impairs bioenergetics by disturbing succinate and glutamate oxidation and induces mitochondrial permeability transition pore opening in rat cerebellum.
J Neurochem
; 158(2): 262-281, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33837559
2.
Experimental evidence that maleic acid markedly compromises glutamate oxidation through inhibition of glutamate dehydrogenase and α-ketoglutarate dehydrogenase activities in kidney of developing rats.
Mol Cell Biochem
; 458(1-2): 99-112, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31032535
3.
High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems.
J Cell Biochem
; 119(9): 7678-7686, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29923625
4.
cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca(2+) homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency.
Biochim Biophys Acta
; 1857(9): 1363-1372, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27240720
5.
Uncoupling, metabolic inhibition and induction of mitochondrial permeability transition in rat liver mitochondria caused by the major long-chain hydroxyl monocarboxylic fatty acids accumulating in LCHAD deficiency.
Biochim Biophys Acta
; 1847(6-7): 620-8, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25868874
6.
2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria.
J Neurochem
; 137(1): 62-75, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26800654
7.
Glycine disrupts myelin, glutamatergic neurotransmission, and redox homeostasis in a neonatal model for non ketotic hyperglycinemia.
Biochimie
; 219: 21-32, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37541567
8.
Functional hypoxia reduces mitochondrial calcium uptake.
Redox Biol
; 71: 103037, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401291
9.
Disruption of Bioenergetics in the Intestine of Wistar Rats Caused by Hydrogen Sulfide and Thiosulfate: A Potential Mechanism of Chronic Hemorrhagic Diarrhea in Ethylmalonic Encephalopathy.
Cell Biochem Biophys
; 81(4): 683-695, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37589888
10.
Ethylmalonic acid impairs brain mitochondrial succinate and malate transport.
Mol Genet Metab
; 105(1): 84-90, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22133302
11.
Reduction of Na+, K+-ATPase activity and expression in cerebral cortex of glutaryl-CoA dehydrogenase deficient mice: a possible mechanism for brain injury in glutaric aciduria type I.
Mol Genet Metab
; 107(3): 375-82, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22999741
12.
Marked reduction of Na(+), K(+)-ATPase and creatine kinase activities induced by acute lysine administration in glutaryl-CoA dehydrogenase deficient mice.
Mol Genet Metab
; 107(1-2): 81-6, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22578804
13.
Impairment of mitochondrial bioenergetics and permeability transition induction caused by major long-chain fatty acids accumulating in VLCAD deficiency in skeletal muscle as potential pathomechanisms of myopathy.
Toxicol In Vitro
; 62: 104665, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31629068
14.
Disturbance of mitochondrial functions associated with permeability transition pore opening induced by cis-5-tetradecenoic and myristic acids in liver of adolescent rats.
Mitochondrion
; 50: 1-13, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31655165
15.
Disturbance of bioenergetics and calcium homeostasis provoked by metabolites accumulating in propionic acidemia in heart mitochondria of developing rats.
Biochim Biophys Acta Mol Basis Dis
; 1866(5): 165682, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31931102
16.
Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum.
Mitochondrion
; 47: 141-150, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30399433
17.
S-Adenosylmethionine Promotes Oxidative Stress and Decreases Na+, K+-ATPase Activity in Cerebral Cortex Supernatants of Adolescent Rats: Implications for the Pathogenesis of S-Adenosylhomocysteine Hydrolase Deficiency.
Mol Neurobiol
; 55(7): 5868-5878, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101646
18.
Metabolite accumulation in VLCAD deficiency markedly disrupts mitochondrial bioenergetics and Ca2+ homeostasis in the heart.
FEBS J
; 285(8): 1437-1455, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476646
19.
Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria.
Neurochem Int
; 108: 133-145, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28284974
20.
α-Ketoadipic Acid and α-Aminoadipic Acid Cause Disturbance of Glutamatergic Neurotransmission and Induction of Oxidative Stress In Vitro in Brain of Adolescent Rats.
Neurotox Res
; 32(2): 276-290, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28429309